WebMethotrexate. Trimethoprim is an antibiotic. It is from a class of medications called antimetabolites. Formula: C14H18N4O3. Formula: C20H22N8O5. Used for treatment of … http://jacobsonandassoc.com/bactrim-toxicity
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WebOct 12, 2024 · a skin rash, no matter how mild; or. high potassium level -- nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. Common side effects … WebDrug interactions associated with trimethoprim include: Methotrexate (a folate antagonist) — several cases of bone marrow suppression have been reported (some fatal) [Baxter, 2013]. Azathioprine — increased risk of haematological toxicity has been reported in some people with a renal transplant who are taking azathioprine — particularly if both drugs are … faze kalei setup
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WebNov 28, 2024 · Sulfamethoxazole is hepatically metabolized by the CYP450 system; it is a CYP2C9 inhibitor. Its half-life is 6 to 12 hours, increasing to between 20 and 50 hours in renal failure. Trimethoprim has a half-life of 8 to 10 hours, is minimally metabolized in the liver, and is primarily excreted in the urine, essentially unchanged. WebPrescribe trimethoprim with caution in people: With impaired renal function. With hyperkalaemia, or taking medication that is known to cause hyperkalaemia. With acute … WebFeb 1, 2024 · swelling of the face, hands, legs, and feet. unsteadiness, trembling, or other problems with muscle control or coordination. weakness in the hands or feet. weakness … fazekas